Which of the following statements regarding buffers are true?

1. Buffers prevent rapid, drastic changes in the pH of body fluids.
2. Buffers systems are designed to stabilize pH within a few hours.
3. Strong acids lower pH more than weak acids because they contribute fewer hydrogen ions (H+).
4. Proteins can buffer both acids and bases.
5. Hemoglobin is an important buffer in red blood cells.

a) 1, 2, 3 and 5

b) 1, 3, 4 and 5

c) 1, 3 and 5

d) 1, 4 and 5

e) 2, 3 and 5