Mr. Wayne is a 38 years man with a significant faamily history of elevated cholesterol levels. his father died at age 42 from a massive heart attack secondary to elevated cholesterol and triglycerides, and two of his older siblings are currently taing medications to lower their cholesterol levels. Mr. Wayne makes an appointment to discuss his risk for hypercholesterolemia. the nurse recognises that Mr Wayne is at risk for family hypercholesterolemia because this is an autosomal dominant inherited condition. (Learning Objective)

a. describe the pattern of autosomal dominant inheritance.

b. Mr. Wayne asks what chance his children have of developing familial hypercholesterlemia. how should the nurse respond?

c. Explan the phenomenon of penentrance observed in autosomal deminant iheritance.