Must use resources provided as well as outside resources.

ASSIGNMENT:

Address the following Short Answer prompts for your Assignment. Be sure to include references to the Learning Resources for this week.

1. In 3 or 4 sentences, explain the appropriate drug therapy for a patient who presents with MDD and a history of alcohol abuse. Which drugs are contraindicated, if any, and why? Be specific. What is the timeframe that the patient should see resolution of symptoms?
2.  
3. List 4 predictors of late onset generalized anxiety disorder.
4.  
5. List 4 potential neurobiology causes of psychotic major depression.
6.  
7. An episode of major depression is defined as a period of time lasting at least 2 weeks. List at least 5 symptoms required for the episode to occur. Be specific.
8.  
9. List 3 classes of drugs, with a corresponding example for each class, that precipitate insomnia. Be specific.

RESOURCES:

• Stahl, S. M. (2021). Stahl’s essential psychopharmacology: Neuroscientific basis and practical applications (5th Ed.) Cambridge University Press.
  • Chapter 10, “Disorders of Sleep and Wakefulness and Their Treatment: Neurotransmitter Networks for Histamine and Orexin” (pp. 401-448)
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• American Psychiatric Association. (2022). Diagnostic and statistical manual of mental disordersLinks to an external site. (5th ed., text rev.). https://go.openathens.net/redirector/waldenu.edu?url=https://dsm.psychiatryonline.org/doi/book/10.1176/appi.books.9780890425787
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• Fernandez-Mendoza, J., & Vgontzas, A. N. (2013). Insomnia and its impact on physical and mental health. Current Psychiatry ReportsLinks to an external site., 15(12), 418. https://doi.org/10.1007/s11920-012-0418-8
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• Levenson, J. C., Kay, D. B., & Buysse, D. J. (2015). The pathophysiology of insomnia. ChestLinks to an external site., 147(4), 1179–1192. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388122/
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• Morgenthaler, T. I., Kapur, V. K., Brown, T. M., Swick, T. J., Alessi, C., Aurora, R. N., Boehlecke, B., Chesson, A. L., Friedman, L., Maganti, R., Owens, J., Pancer, J., & Zak, R. (2007). Practice parameters for the treatment of narcolepsy and other hypersomnias of central origin. SLEEPLinks to an external site., 30(12), 1705–1711. https://j2vjt3dnbra3ps7ll1clb4q2-wpengine.netdna-ssl.com/wp-content/uploads/2017/07/PP_Narcolepsy.pdf
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• Morgenthaler, T. I., Owens, J., Alessi, C., Boehlecke, B, Brown, T. M., Coleman, J., Friedman, L., Kapur, V. K., Lee-Chiong, T., Pancer, J., & Swick, T. J. (2006). Practice parameters for behavioral treatment of bedtime problems and night wakings in infants and young children. SLEEPLinks to an external site., 29(1), 1277–1281. https://j2vjt3dnbra3ps7ll1clb4q2-wpengine.netdna-ssl.com/wp-content/uploads/2017/07/PP_NightWakingsChildren.pdf
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• Sateia, M. J., Buysse, D. J., Krystal, A. D., Neubauer, D. N., & Heald, J. L. (2017). Clinical practice guideline for the pharmacologic treatment of chronic insomnia in adults: An American Academy of Sleep Medicine clinical practice guideline. Journal of Clinical Sleep MedicineLinks to an external site., 13(2), 307–349. https://jcsm.aasm.org/doi/pdf/10.5664/jcsm.6470
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• Winkleman, J. W. (2015). Insomnia disorder. The New England Journal of MedicineLinks to an external site., 373(15), 1437–1444. https://doi.org/10.1056/NEJMcp1412740

Address the following Short Answer prompts for your Assignment. Be sure to include references to the Learning Resources for this week.

RESOURCES:

• Stahl, S. M. (2021). Stahl’s essential psychopharmacology: Neuroscientific basis and practical applications (5th Ed.) Cambridge University Press.
  • Chapter 1, “Chemical Neurotransmission”  (pp. 1-28)

• Mental Health TV. (2022, Oct 7).  Psychopharmacology-Module oneLinks to an external site. [Video]. YouTube. https://www.youtube.com/watch?v=Ku8PZlXAYco
• Mental Health TV. (2022, Oct 7).  Psychopharmacology-Module twoLinks to an external site. [Video]. YouTube. https://www.youtube.com/watch?v=jw9uc4qVqew
• Mental Health TV. (2022, Oct 7).  Psychopharmacology-Module threeLinks to an external site. [Video]. YouTube. https://www.youtube.com/watch?v=xLGfB3E4rqE&t=523s

ASSIGNMENT:

1. 1.) In 4 or 5 sentences, describe the anatomy of the basic unit of the nervous system, the neuron. Include each part of the neuron and a general overview of electrical impulse conduction, the pathway it travels, and the net result at the termination of the impulse. Be specific and provide examples.
2.  
3. 2.) Answer the following (listing is acceptable for these questions):
   • What are the major components that make up the subcortical structures?
   • Which component plays a role in learning, memory, and addiction?
   • What are the two key neurotransmitters located in the nigra striatal region of the brain that play a major role in motor control?
   •  
4. 3.) In 3 or 4 sentences, explain how glia cells function in the central nervous system. Be specific and provide examples.
5.  
6. 4.) The synapse is an area between two neurons that allows for chemical communication. In 3 or 4 sentences, explain what part of the neurons are communicating with each other and in which direction does this communication occur? Be specific.
7.  
8. 5.) In 3–5 sentences, explain the concept of “neuroplasticity.” Be specific and provide examples.