Serotonin is a naturally occurring neurotransmitter that has a role in determining mood and emotions. A

shortage of serotonin has been linked to phobias, schizophrenia, aggressive behaviour, depression,

uncontrolled appetite, and migraine headaches. Several types of drugs affect serotonin levels:

o Prozac, Paxil, Zoloft – cause serotonin to remain longer in the brain.

o Clozapine – prevents serotonin from binding to the postsynaptic membranes.

o Hallucinogens (LSD, ecstasy) – react directly with the serotonin receptors to produce the same

effect as serotonin.

a) Why is Prozac prescribed for people with depression?

b) Which drug should not be taken by someone experiencing clinical depression?