2)You are intending to prescribe your patient 2 medications: drug X and drug Y. The patient is a 77-year-old female with a past medical history of type-2 diabetes, hypertension, and CKD III-IV. She recently had geriatric pharmacogenomic testing done and was found to have a hyperactive CYP 3A4 gene presentation (which is sometimes referred to as an extensive or hyper metabolizer). You see that drug X is almost exclusively renally cleared. You also see that drug Y is extensively hepatically metabolized. Based on this info, what would you expect in terms of blood concentrations of both drugs after administration? Would you think any dose adjustments would be necessary, and if so how might you adjust them?
1. What challenges does a country face…
* With a very high percentage of young people?
* With a very high percentage of old people?
2. Considering the extremely low birthrates in highly developed countries, should people be encouraged to have more children?
* Why or why not?
3. Discuss the effectiveness of 2 strategies to reduce birthrates in developing countries. What are some barriers, and why:
* Improving the status of women
4. What do you think would be more effective in minimizing the impacts of humans on the planet:
* Controlling population growth in developing nations (where most growth is occurring) and/or
* Curbing consumption of resources in developed countries (where the impact per person is highest)?
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