E. How to Prepare the REVIEW of the article “ Mutant p53: One name, many proteins”

• Read the scientific article. Make notes summarizing key ideas and noting critical portions of the text.
• The review should be 5 pages, single-spaced or 1.5 spaces using a standard 12-point font (such as Times New Roman).
• As before, please include no more than one figure. FOR THIS REVIEW IT WILL BE FIGURE 2.
• Please address the following points in your review:
  • In 300-500 describe the “Gain of Function Hypothesis”. Include and discuss the hypothesis in light of Figure 2 (which you should include in your review).
  • Use FIGURE 2 as the CENTRAL FOCUS of you review.
  • From Table 2, select one (1) CATEGORY of transcriptionally activated genes (such as “increased proliferation”) and in 300-500 words discuss how p53 might regulate your selected ‘cellular phenotype’.
  • Include a short description of the final section “p52 and therapeutic approaches”.