MAKE A GRAPH OF THE FOLLOWING Enzyme E shows cooperativity as substrate [S] increases. X is a positive allosteric effector, Y is a negative allosteric effector. Label axes and draw and label the indicated curves of rxn velocity V vs [S].

a. no X or Y is present.

b. X is added

c. Y is added

d. a mutation locks E in the T state

e. a mutation locks E in the R state