Grave’s disease is caused by the overproduction of immunoglobulins that mimic the shape of TSH and thereby bind to the TSH receptors. What is the expected hormonal change to the overproduction of TSH mimicking immunoglobulins? 

Select one:

a. a decrease in the production of TRH and an increase in the metabolic rate 

b. an increase in the production of TRH and an increase in the metabolic rate

c. a decrease in the production of TSH, and a decrease in the metabolic rate

d. an increase in the production of TSH, and a decrease in the metabolic rate