G Protein-Coupled Receptors and Receptor Tyrosine Kinases 

Exercise Objectives

• Explore the structure of a G protein-receptor complex.
• Explore the conformational changes in a receptor tyrosine kinase.

Resources & Websites

• Bioinformatics Exercises 4.4, 4.5, 5.1, and 5.3
• Figures 10.3 to 10.5, Chapter 10
• Overview of Adrenergic Receptors: Molecule of the Month in the PDB:

http://pdb.org/pdb/101/motm.do?momID=100

• Protein Data Bank:

http://www.rcsb.org

• Protein Workshop Tutorial:

http://www.rcsb.org/pdb/staticHelp.do?p=help/viewers/proteinWorkshop_viewer.html