DESCRIBE THE ABSORPTION OF COBALAMIN (VITAMIN B12) IN THE NORMAL HEALTHY CAT.Discuss the mechanisms by which intestinal and extra-intestinal abnormalities
can cause cobalamin deficiency in the cat.

a) Describe the absorption of cobalamin (vitamin B12) in the normal healthy cat.
(12 marks)
b) Describe the function(s) of cobalamin (vitamin B12) in the normal healthy cat.
(12 marks)
c) Discuss the mechanisms by which intestinal and extra-intestinal abnormalities
can cause cobalamin deficiency in the cat. (24 marks)
2. Answer all parts of this question:
a) Outline the current understanding of the etiology and pathophysiology of feline
hypertrophic obstructive cardiomyopathy (HOCM) and its effect on cardiac
function. (15 marks)
b) Describe the role of cardiac troponin I (cTnI) and brain natriuretic peptide (BNP)
in normal cardiac function. Also describe how cTnI and n-terminal pro-BNP are
affected by cardiac and non-cardiac factors. (15 marks)
c) For cats with hypertrophic cardiomyopathy, list three (3) measurements on twodimensional
(2D) and/or motion mode (M-mode) echocardiography that have
been associated with prognosis. Briefly describe how each might affect outcome.
(9 marks)
d) The ratio of left atrial to aortic dimensions on a right parasternal short-axis view
is frequently used to assess volume loading of the left heart. Discuss the
strengths and weaknesses of this measurement. (9 marks)
Continued over page
Feline Medicine Paper 1 Page 3 of 4
3. Answer both parts of this question:
a) Discuss the proposed mechanisms for the aetiopathogenesis of feline
inflammatory bowel disease (IBD). (24 marks)
b) Describe all the features that may assist in the differentiation of a case of
gastrointestinal low-grade (small cell) alimentary lymphoma from severe IBD.
(24 marks)

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