Biosignaling and the KEGG Database

Exercise Goals

• Learn how to use the KEGG database.
• Describe the relationships between receptors, kinases, and cellular functions in biosignaling.

Difficulty

• 13 questions
• Computer-Related: Easy 
• Subject-Related: Moderate

Resources & Websites

• Kyoto Encyclopedia of Genes and Genomes (KEGG):

http://www.kegg.jp

• Description of the KEGG database:

http://www.kegg.jp/kegg/kegg1.html

Exercise

As inferred from Chapter 10, the many processes of biosignaling represent a complex fabric of interconnected pathways that regulate cellular function. The Kyoto Encyclopedia of Genes and Genomes (KEGG) provides a means to visualize these pathways and to obtain information about the associated proteins and genes. In this exercise, information from the KEGG databases will be analyzed to explore the insulin and MAPK signaling pathways.

Instructions

1. Go to