Aspirin and NSAIDs are causative factors for the development of peptic ulcer disease because they:

A.   Increase acid secretion

B.    Allow proliferation of H. pylori

C.    Damage the mucosal barrier

D.   Alter platelet aggregation

Rationale and Reference please

This is one of a self assessment tool I need to do and am requesting tutor assistant to be sure my answer is correct> What is this?