3)Let’s explore BPG binding by hemoglobin a bit further! Download the PDB file for hemoglobin
bound to BPG (PDB: 1B86) and open it up in PyMOL. Hint: You can color the individual subunits
differently in order to most easily visualize the quaternary structure of hemoglobin. One way to do
this is to click on the selection line for the PDB (1B86), then click on menu button C (for color) and
select ‘by chain’.
a)Explain why we call BPG a “heterotropic allosteric modulator” of hemoglobin.
Hi there! Click one of our representatives below and we will get back to you as soon as possible.